📢 ICH E6(R3) GCP Annex 2 was finalized and published by ICH on 3 June 2026. It covers pragmatic and decentralized elements, as well as the use of real-world data (RWD)—topics frequently discussed in CDDF meetings. The guidance also offers valuable insights into thinking about proportionate approaches in clinical trials.
Read the full document here: https://database.ich.org/sites/default/files/ICH_E6(R3)_Annex%202_Guideline_Step%204_2026_0603_0.pdf