The Cancer Drug Development Forum – CDDF is the platform for all stakeholders involved in the development of cancer drugs.

BDA Workshop Minimal Residual Disease: End-Points in Clinical Trials


In March 2014 the European Medicines Agency (EMA) published a draft guidance considering the role of pathological Complete Response (pCR) as an endpoint in neoadjuvant breast cancer studies.

On May 13 and 14, 2014, the Cancer Drug Development Forum (CDDF), then named Biotherapy Development Association (BDA), met in London to debate the draft guidance. In addition to endpoints in neoadjuvant breast cancer,  the meeting, attended by  delegates from academia, industry and the regulatory authorities, also considered minimal residual disease (MRD) in chronic lymphocytic leukaemia (CLL) and other haematological malignancies. A draft EMA document on MRD as an endpoint in CLL is expected in July. Please find the meeting report here.

Download the programme of the “Minimal Residual Residual Disease” Workshop here.

To have access to the workshop presentations, please contact CDDF Headquarters at

Cancer Drug Development Forum
c/o BLSI
Clos Chapelle-aux-Champs 30
1200 Brussels, Belgium
Tel: +32 2 880 62 70

Legal address
c/o Deloitte Tirol
Wirtschaftsprüfungs GmbH,
Wilhelm-Greil-Str. 15,
6020 Innsbruck, Austria