CDDF Multi-Stakeholder Workshop New Modalities in Oncology Drug Development 31 March – 1 April 2025, Hybrid Workshop Recordings SESSION 1: WHAT'S NEW IN ONCOLOGY Session 1 – complete Recent Advances In Antibody Drug Conjugates – Mike Seganish (MSD, US) – talk was given by Stefan Symeonides (CDDF, UK) on behalf of Mike Seganish Bispecific and their variants; T cell engagers – Ulrike Philippar (Johnson & Johnson, BE) New Opportunities in Undruggable Targets Using TPD – Ian Churcher (Janus Drug Discovery, UK) SESSION 2: RADIOPHARMACEUTICALS Session 2 – complete Access and basic principles of radiopharmaceuticals – Viktor Grünwald (University Hospital Essen, DE) Advancements in Radiopharmaceutical and emerging guidance – Oliver Kiß (Helmholtz-Zentrum Dresden-Rossendorf, DE) From Bench to Bedside: Innovations in Radionuclide Therapy for Solid Tumors- The latest breakthroughs in radionuclide/ radiopharmaceutical treatments – Christophe Deroose (UZ Leuven, BE) SESSION 3: PERSONALISED VACCINES IN ONCOLOGY Session 3 – complete Short overview, including vector technology, types of antigens – Samra Turajlic (Francis Crick Institute; the Royal Marsden, UK) Individualized Neoantigen Therapy: The needle-to-needle process – Clemens Krepler (MSD, US) Personalised treatments from regulatory perspective – Olga Kholmanskikh (FAMHP, BE) SESSION 4: CELLULAR THERAPIES Session 4 – complete Cellular therapies and GMOs: What is out there and pipeline – Vladimir Galvao (Vall d’Hebron Institute of Oncology, ES) Delivery of them: Learnings from CAR T cells – Tobias Menne (Newcastle University, UK) 15 years of ATMPs: EU regulatory framework – Caroline Pothet (EMA, NL) SESSION 5: WRAP UP PANEL DISCUSSION Session 5 – complete